Ser154
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Home > Phosphorylation Site Page: > Ser154  -  VASP (rat)

Site Information
EHLERRVsNAGGPPA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448379

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 4 ) , mutation of modification site ( 3 ) , phospho-antibody ( 1 , 2 , 3 , 4 ) , western blotting ( 1 , 2 , 3 , 4 )
Relevant cell line - cell type - tissue:
'muscle, smooth'-'heart, artery' ( 4 ) , BAEC (endothelial) ( 3 ) , cerebral artery ( 2 ) , mesangial-kidney ( 1 ) , vascular smooth muscle cell ('muscle, smooth') [eNOS (cow)] ( 3 )

Upstream Regulation
Regulatory protein:
eNOS (human) ( 3 )
Putative in vivo kinases:
PKCA (rat) ( 4 )
Kinases, in vitro:
PKCA (rat) ( 4 )
Treatments:
8-Rp-cAMP ( 4 ) , angiotensin_2 ( 3 ) , colforsin ( 4 ) , DPI ( 1 ) , GF109203X ( 4 ) , Go_6976 ( 4 ) , Go_6983 ( 4 ) , H2O2 ( 1 ) , L-NAME ( 2 ) , PDGF ( 1 ) , phorbol_ester ( 4 ) , Rp-cGMP ( 4 ) , serum ( 4 ) , SNAP ( 4 )

References 

1

Eisel F, et al. (2013) Platelet-derived growth factor triggers PKA-mediated signalling by a redox-dependent mechanism in rat renal mesangial cells. Biochem Pharmacol 85, 101-8
23103565   Curated Info

2

Neppl RL, et al. (2009) Thromboxane A2-induced bi-directional regulation of cerebral arterial tone. J Biol Chem 284, 6348-60
19095646   Curated Info

3

Suzuki H, et al. (2006) Activation of endothelial nitric oxide synthase by the angiotensin II type 1 receptor. Endocrinology 147, 5914-20
16980435   Curated Info

4

Chitaley K, et al. (2004) Vasodilator-stimulated phosphoprotein is a substrate for protein kinase C. FEBS Lett 556, 211-5
14706852   Curated Info