Ser2016
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Home > Phosphorylation Site Page: > Ser2016  -  CACNA1B (rat)

Site Information
TQPAPNAsPMKRSIS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25792205

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
neuron-'brain, hippocampus' [CDK5 (mouse), homozygous knockout] ( 1 )

Upstream Regulation
Putative in vivo kinases:
CDK5 (mouse) ( 1 )
Kinases, in vitro:
CDK5 (human) ( 1 )

Downstream Regulation
Effects of modification on CACNA1B:
protein conformation ( 1 )
Induce interaction with:
RIMS1 (human) ( 1 )

References 

1

Su SC, et al. (2012) Regulation of N-type Voltage-Gated Calcium Channels and Presynaptic Function by Cyclin-Dependent Kinase 5. Neuron 75, 675-87
22920258   Curated Info