Thr818
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Home > Phosphorylation Site Page: > Thr818  -  FLI (human)

Site Information
LHRPRHAtVSRsLEG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25787600

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
32D (myeloid) ( 2 ) , breast cell-breast ( 1 ) , HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 2 ) , MMTV-PyMT (breast cell) ( 1 )

Upstream Regulation
Kinases, in vitro:
SGK3 (human) ( 2 )

Downstream Regulation
Effects of modification on biological processes:
transcription, induced ( 2 )

References 

1

He JP, et al. (2018) Flightless-I blocks p62-mediated recognition of LC3 to impede selective autophagy and promote breast cancer progression. Cancer Res
29898994   Curated Info

2

Xu J, et al. (2009) Identification of Flightless-I as a substrate of the cytokine-independent survival kinase CISK. J Biol Chem 284, 14377-85
19293151   Curated Info