Ser561
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Home > Phosphorylation Site Page: > Ser561  -  PSD-95 (rat)

Site Information
EFPDkFGsCVPHTTR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25680400

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , neuron-'brain, hippocampus' ( 1 )

Upstream Regulation
Treatments:
4-AP ( 1 ) , picrotoxin ( 1 )

Downstream Regulation
Effects of modification on PSD-95:
protein conformation ( 1 )
Induce interaction with:
PSD-95 (rat) ( 1 )

References 

1

Wu Q, Sun M, Bernard LP, Zhang H (2017) Postsynaptic density 95 (PSD-95) serine 561 phosphorylation regulates a conformational switch and bidirectional dendritic spine structural plasticity. J Biol Chem 292, 16150-16160
28790172   Curated Info