Ser238
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Home > Phosphorylation Site Page: > Ser238  -  MCR (human)

Site Information
QGTPLTCsPNVENRG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25692902

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
leukemia ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
ERK1 (human) ( 1 ) , ERK2 (human) ( 1 )
Kinases, in vitro:
ERK1 (human) ( 1 )
Treatments:
aldosterone ( 1 ) , FR180204 ( 1 ) , PD98059 ( 1 )

Downstream Regulation
Effects of modification on MCR:
protein degradation ( 1 ) , ubiquitination ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )

References 

1

Faresse N, Vitagliano JJ, Staub O (2012) Differential ubiquitylation of the mineralocorticoid receptor is regulated by phosphorylation. FASEB J 26, 4373-82
22798426   Curated Info