Tyr215
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Home > Phosphorylation Site Page: > Tyr215  -  SDHA (human)

Site Information
SLRYDTSyFVEYFAL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25682901

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Disease tissue studied:
glioblastoma multiforme ( 1 ) , glioma ( 1 )
Relevant cell line - cell type - tissue:
neuron-'brain, cerebral cortex' ( 1 ) , T98G (glial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
Src (human) ( 1 )
Kinases, in vitro:
Src (human) ( 1 )
Treatments:
PP2 ( 1 )

Downstream Regulation
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )

References 

1

Ogura M, Yamaki J, Homma MK, Homma Y (2012) Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components. Biochem J 447, 281-9
22823520   Curated Info