Ser665
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Home > Phosphorylation Site Page: > Ser665  -  CDH5 (human)

Site Information
yDVSVLNsVRRGGAK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2562900

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 1 , 2 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HUVEC (endothelial) ( 1 ) , skin ( 2 ) , SVEC (endothelial) ( 2 )

Upstream Regulation
Regulatory protein:
RRas (human) ( 1 )
Treatments:
angiopoietin-1 ( 2 ) , VEGF ( 1 , 2 )

Downstream Regulation
Effects of modification on CDH5:
intracellular localization ( 2 )

References 

1

Sawada J, et al. (2012) Small GTPase R-Ras Regulates Integrity and Functionality of Tumor Blood Vessels. Cancer Cell 22, 235-49
22897853   Curated Info

2

Gavard J, Patel V, Gutkind JS (2008) Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia. Dev Cell 14, 25-36
18194650   Curated Info