Tyr441
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Home > Phosphorylation Site Page: > Tyr441  -  AMPKA1 (rat)

Site Information
EWKVVNPyYLRVRRK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 457338

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293T (epithelial) ( 1 ) , 3T3 (fibroblast) ( 1 ) , HeLa (cervical) ( 1 )

Downstream Regulation
Effects of modification on AMPKA1:
enzymatic activity, inhibited ( 1 )

References 

1

Yamada E, et al. (2016) Fyn phosphorylates AMPK to inhibit AMPK activity and AMP-dependent activation of autophagy. Oncotarget 7, 74612-74629
27626315   Curated Info