Thr305
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Home > O-GlcNAc Site Page: > Thr305  -  Akt1 (human)

Site Information
EGIkDGAtMKtFCGt   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25538002

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
breast cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
PUGNAc ( 1 )

Downstream Regulation
Effects of modification on Akt1:
enzymatic activity, inhibited ( 1 ) , phosphorylation ( 1 )

References 

1

Wang S, et al. (2012) Extensive Crosstalk between O-GlcNAcylation and Phosphorylation Regulates Akt Signaling. PLoS One 7, e37427
22629392   Curated Info