Thr143
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Home > Phosphorylation Site Page: > Thr143  -  p57Kip2 iso2 (mouse)

Site Information
AEPTPPAtPAPASDL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25525402

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 )

Upstream Regulation
Putative in vivo kinases:
P38A (human) ( 1 )
Kinases, in vitro:
P38A (human) ( 1 )
Treatments:
BIRB-0796 ( 1 ) , H2O2 ( 1 ) , ionomycin ( 1 ) , SB203580 ( 1 ) , UV ( 1 )

Downstream Regulation
Effects of modification on p57Kip2 iso2:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell cycle regulation ( 1 )
Induce interaction with:
CDK2 (human) ( 1 )

References 

1

Joaquin M, et al. (2012) The p57 CDKi integrates stress signals into cell-cycle progression to promote cell survival upon stress. EMBO J 31, 2952-64
22569127   Curated Info

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