Thr208
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Home > Phosphorylation Site Page: > Thr208  -  Snail2 (human)

Site Information
QGHIRtHtGEkPFSC   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25311911

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 1 ) , mass spectrometry ( 2 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
Jurkat (T lymphocyte) ( 2 ) , SAS (squamous) ( 1 )

Upstream Regulation
Putative in vivo kinases:
LATS1 (human) ( 1 ) , LATS2 (human) ( 1 )
Kinases, in vitro:
LATS1 (human) ( 1 ) , LATS2 (human) ( 1 )
Treatments:
siRNA ( 1 )

Downstream Regulation
Effects of modification on Snail2:
protein stabilization ( 1 )
Effects of modification on biological processes:
carcinogenesis, induced ( 1 ) , cell motility, induced ( 1 )

References 

1

Fujibayashi E, et al. (2022) LATS kinases and SLUG regulate the transition to advanced stage in aggressive oral cancer cells. Sci Rep 12, 12363
35859006   Curated Info

2

Possemato A (2008) CST Curation Set: 3661; Year: 2008; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS:pSXXXpS
Curated Info

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