Ser134
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Home > Phosphorylation Site Page: > Ser134  -  OBFC2B (human)

Site Information
NDSNPSAsQPTTGPS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25302960

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 , 2 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
leukemia ( 2 ) , chronic myelogenous leukemia ( 2 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , HeLa (cervical) ( 1 ) , K562 (erythroid) ( 2 )

Upstream Regulation
Putative in vivo kinases:
DNAPK (human) ( 1 )
Kinases, in vitro:
DNAPK (human) ( 1 )
Treatments:
aphidicolin ( 1 ) , calyculin_A ( 1 ) , camptothecin ( 1 ) , hydroxyurea ( 1 ) , ionizing_radiation ( 1 ) , okadaic_acid ( 1 )

Downstream Regulation
Effects of modification on biological processes:
DNA repair, induced ( 1 )

References 

1

Ashton NW, et al. (2017) hSSB1 phosphorylation is dynamically regulated by DNA-PK and PPP-family protein phosphatases. DNA Repair (Amst) 54, 30-39
28448822   Curated Info

2

Possemato A (2007) CST Curation Set: 2723; Year: 2007; Biosample/Treatment: cell line, K562/untreated; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]XP Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser) 14-3-3 Binding Motif (4E2) Mouse mAb Cat#: 9606
Curated Info

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