Thr265
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Home > Phosphorylation Site Page: > Thr265  -  AKAP4 (human)

Site Information
KERISPRtPAsKIAs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 457176

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 , 2 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
spermatozoa ( 1 , 2 )

Upstream Regulation
Putative in vivo kinases:
ERK2 (human) ( 1 )
Kinases, in vitro:
ERK2 (human) ( 1 )

Downstream Regulation
Effects of modification on AKAP4:
intracellular localization ( 1 )

References 

1

Rahamim Ben-Navi L, et al. (2016) A-Kinase Anchoring Protein 4 (AKAP4) is an ERK1/2 substrate and a switch molecule between cAMP/PKA and PKC/ERK1/2 in human spermatozoa. Sci Rep 6, 37922
27901058   Curated Info

2

Ficarro S, et al. (2003) Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation. J Biol Chem 278, 11579-89
12509440   Curated Info