Thr618
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Home > Phosphorylation Site Page: > Thr618  -  TEX14 (human)

Site Information
EEASSPStGQPSLCS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25158902

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 1 )

Upstream Regulation
Putative in vivo kinases:
CDK1 (human) ( 1 )
Treatments:
nocodazole ( 1 ) , RO-3306 ( 1 )

Downstream Regulation
Effects of modification on TEX14:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Induce interaction with:
PLK1 (human) ( 1 )

References 

1

Mondal G, et al. (2012) Tex14, a Plk1-regulated protein, is required for kinetochore-microtubule attachment and regulation of the spindle assembly checkpoint. Mol Cell 45, 680-95
22405274   Curated Info

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