Lys480
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Home > Sumoylation Site Page: > Lys480  -  SERCA2 (human)

Site Information
SVIkQLMkkEFtLEF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25092201

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , heart ( 1 ) , myocyte ( 1 )

Downstream Regulation
Effects of modification on SERCA2:
enzymatic activity, induced ( 1 ) , molecular association, regulation ( 1 ) , protein stabilization ( 1 ) , ubiquitination ( 1 )
Induce interaction with:
Other ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
cardiomyopathy ( 1 )

References 

1

Kho C, et al. (2011) SUMO1-dependent modulation of SERCA2a in heart failure. Nature 477, 601-5
21900893   Curated Info

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