Thr1618
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Thr1618  -  POLR2A (human)

Site Information
QSPSysPtsPsYSPT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25042600

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , phospho-antibody ( 1 ) , phosphoamino acid analysis ( 2 ) , western blotting ( 1 , 2 )
Disease tissue studied:
lymphoma ( 1 , 2 ) , B cell lymphoma ( 2 ) , Burkitt's lymphoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CDK9 (human) ( 2 )

References 

1

Schüller R, et al. (2016) Heptad-Specific Phosphorylation of RNA Polymerase II CTD. Mol Cell 61, 305-14
26799765   Curated Info

2

Hsin JP, Sheth A, Manley JL (2011) RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing. Science 334, 683-6
22053051   Curated Info