Thr24
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Home > Phosphorylation Site Page: > Thr24  -  FOXO1A (rat)

Site Information
LPRQRSCtWPLPRPE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448560

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Disease tissue studied:
liver cancer ( 2 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 2 ) , H4IIe (hepatic) ( 2 ) , L6 (myoblast) ( 1 )

Upstream Regulation
Kinases, in vitro:
Akt1 (rat) ( 2 )
Treatments:
API-2 ( 1 ) , D4476 ( 2 ) , insulin ( 1 , 2 ) , PIK90 ( 1 ) , PP242 ( 1 ) , rapamycin ( 1 )

References 

1

Feldman ME, et al. (2009) Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol 7, e38
19209957   Curated Info

2

Rena G, Bain J, Elliott M, Cohen P (2004) D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a. EMBO Rep 5, 60-5
14710188   Curated Info