Ser1710
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Home > Phosphorylation Site Page: > Ser1710  -  MAP2 (human)

Site Information
HVTsKCGsLKNIRHR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 456809

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry (in vitro) ( 1 ) , microscopy-colocalization with upstream kinase ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PKACA (human) ( 1 )
Kinases, in vitro:
PKACA (human) ( 1 )

Downstream Regulation
Effects of modification on MAP2:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 1 )
Induce interaction with:
ACTB (human) ( 1 ) , TUBA1A (human) ( 1 )

References 

1

Ozer RS, Halpain S (2000) Phosphorylation-dependent localization of microtubule-associated protein MAP2c to the actin cytoskeleton. Mol Biol Cell 11, 3573-87
11029056   Curated Info

2

Drewes G, et al. (1997) MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption. Cell 89, 297-308
9108484   Curated Info