Lys428
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Home > Sumoylation Site Page: > Lys428  -  CTBP1 (human)

Site Information
PsPGQTVkPEADRDH   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2407413

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 2 ) , immunoprecipitation ( 1 , 2 ) , modification-specific antibody ( 2 ) , mutation of modification site ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 2 ) , HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 1 , 2 ) , MEF (fibroblast) ( 1 )

Upstream Regulation
Regulatory protein:
GSTA1 (human) ( 1 ) , nNOS (human) ( 1 )

Downstream Regulation
Effects of modification on CTBP1:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )
Inhibit interaction with:
nNOS (human) ( 1 )

References 

1

Lin X, et al. (2003) Opposed regulation of corepressor CtBP by SUMOylation and PDZ binding. Mol Cell 11, 1389-96
12769861   Curated Info

2

Kagey MH, Melhuish TA, Wotton D (2003) The polycomb protein Pc2 is a SUMO E3. Cell 113, 127-37
12679040   Curated Info

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