Ser36
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Home > Phosphorylation Site Page: > Ser36  -  GRK7 (human)

Site Information
ELQRRRRsLALPGLQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 456355

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mutation of modification site ( 2 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PKCA (human) ( 1 )
Kinases, in vitro:
PKACA (human) ( 2 )
Treatments:
4alphaPMA ( 1 ) , colforsin ( 1 , 2 ) , IBMX ( 1 ) , NaF ( 1 ) , phorbol_ester ( 1 ) , PKC_inhibitor_myristoylated ( 1 )

Downstream Regulation
Effects of modification on GRK7:
enzymatic activity, inhibited ( 2 )

References 

1

Osawa S, Jo R, Weiss ER (2008) Phosphorylation of GRK7 by PKA in cone photoreceptor cells is regulated by light. J Neurochem 107, 1314-24
18803695   Curated Info

2

Horner TJ, Osawa S, Schaller MD, Weiss ER (2005) Phosphorylation of GRK1 and GRK7 by cAMP-dependent protein kinase attenuates their enzymatic activities. J Biol Chem 280, 28241-50
15946941   Curated Info