Ser382
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Home > Phosphorylation Site Page: > Ser382  -  ELK1 (rat)

Site Information
IHFWSTLsPIAPRSP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447872

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 2 ) , immunoprecipitation ( 1 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 2 , 3 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
GEC (epithelial) ( 3 ) , HEK293T (epithelial) ( 1 ) , NRK49F (fibroblast) ( 2 )

Upstream Regulation
Putative in vivo kinases:
ERK1 (rat) ( 2 )
Treatments:
EGF ( 3 ) , phorbol_ester ( 3 ) , U0126 ( 2 )

Downstream Regulation
Effects of modification on biological processes:
transcription, induced ( 2 )

References 

1

Liu SY, et al. (2019) PIAS1 Ser-503 phosphorylation-mediated Elk-1 SUMOylation promotes neuronal survival in APP/PS1 mice. Br J Pharmacol
30849179   Curated Info

2

Ponnusamy M, et al. (2011) ERK pathway mediates P2X7 expression and cell death in renal interstitial fibroblasts exposed to necrotic renal epithelial cells. Am J Physiol Renal Physiol 301, F650-9
21677150   Curated Info

3

Cybulsky AV, et al. (2005) Activation of the extracellular signal-regulated kinase by complement C5b-9. Am J Physiol Renal Physiol 289, F593-603
15855657   Curated Info

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