Lys11
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Home > Sumoylation Site Page: > Lys11  -  SUMO2 (human)

Site Information
EkPkEGVktENNDHI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2344803

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 4 , 6 , 7 , 9 ) , western blotting ( 7 )
Disease tissue studied:
bone cancer ( 9 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
heat_shock ( 9 )

References 

1

Lumpkin RJ, et al. (2017) Site-specific identification and quantitation of endogenous SUMO modifications under native conditions. Nat Commun 8, 1171
29079793   Curated Info

2

Hendriks IA, et al. (2014) Uncovering global SUMOylation signaling networks in a site-specific manner. Nat Struct Mol Biol 21, 927-36
25218447   Curated Info

3

Impens F, Radoshevich L, Cossart P, Ribet D (2014) Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli. Proc Natl Acad Sci U S A 111, 12432-7
25114211   Curated Info

4

Tammsalu T, et al. (2014) Proteome-wide identification of SUMO2 modification sites. Sci Signal 7, rs2
24782567   Curated Info

5

Galisson F, et al. (2011) A novel proteomics approach to identify SUMOylated proteins and their modification sites in human cells. Mol Cell Proteomics 10, M110.004796
21098080   Curated Info

6

Matic I, et al. (2010) Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif. Mol Cell 39, 641-52
20797634   Curated Info

7

Blomster HA, et al. (2010) In vivo identification of sumoylation sites by a signature tag and cysteine-targeted affinity purification. J Biol Chem 285, 19324-9
20388717   Curated Info

8

Hsiao HH, et al. (2009) "ChopNSpice," a mass spectrometric approach that allows identification of endogenous small ubiquitin-like modifier-conjugated peptides. Mol Cell Proteomics 8, 2664-75
19721078   Curated Info

9

Golebiowski F, et al. (2009) System-wide changes to SUMO modifications in response to heat shock. Sci Signal 2, ra24
19471022   Curated Info

10

Cooper HJ, et al. (2005) Fourier transform ion cyclotron resonance mass spectrometry for the analysis of small ubiquitin-like modifier (SUMO) modification: identification of lysines in RanBP2 and SUMO targeted for modification during the E3 autoSUMOylation reaction. Anal Chem 77, 6310-9
16194093   Curated Info

11

Vertegaal AC, et al. (2004) A proteomic study of SUMO-2 target proteins. J Biol Chem 279, 33791-8
15175327   Curated Info

12

Tatham MH, et al. (2001) Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9. J Biol Chem 276, 35368-74
11451954   Curated Info