Tyr179
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Home > Phosphorylation Site Page: > Tyr179  -  TBK1 (mouse)

Site Information
sLYGTEEyLHPDMYE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 23151249

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , macrophage ( 1 )

Upstream Regulation
Regulatory protein:
A3GALT2 (mouse) ( 1 ) , CD1D (mouse) ( 1 )
Putative in vivo kinases:
Pyk2 (mouse) ( 1 )
Kinases, in vitro:
Pyk2 (mouse) ( 1 )
Treatments:
CpG ( 1 ) , LPS ( 1 ) , poly(I-C) ( 1 ) , siRNA ( 1 )

Downstream Regulation
Effects of modification on TBK1:
phosphorylation ( 1 )
Effects of modification on biological processes:
signaling pathway regulation ( 1 )

References 

1

Liu X, et al. (2019) Glycolipid iGb3 feedback amplifies innate immune responses via CD1d reverse signaling. Cell Res 29, 42-53
30514903   Curated Info