Thr440
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Home > Phosphorylation Site Page: > Thr440  -  TAO1 (human)

Site Information
RNREHFAtIRTAsLV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 23150854

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 3 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , Jurkat (T lymphocyte) ( 3 ) , neuron-'brain, hippocampus' ( 1 )

Upstream Regulation
Putative in vivo kinases:
MST3 (human) ( 1 )

Downstream Regulation
Effects of modification on TAO1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 1 )
Induce interaction with:
DBN1 (human) ( 1 ) , MYL5 (human) ( 1 )

References 

1

Ultanir SK, et al. (2014) MST3 Kinase Phosphorylates TAO1/2 to Enable Myosin Va Function in Promoting Spine Synapse Development. Neuron 84, 968-82
25456499   Curated Info

2

Shiromizu T, et al. (2013) Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project. J Proteome Res 12, 2414-21
23312004   Curated Info

3

Guo A (2011) CST Curation Set: 12061; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pTXR
Curated Info