Tyr133
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Home > Phosphorylation Site Page: > Tyr133  -  PCNA (human)

Site Information
LGIPEQEysCVVkMP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 231166700

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
MEF (fibroblast) ( 1 ) , stem ( 1 )

Upstream Regulation
Putative in vivo kinases:
IGF1R (human) ( 1 )
Kinases, in vitro:
IGF1R (human) ( 1 )

Downstream Regulation
Effects of modification on PCNA:
ubiquitination ( 1 )
Effects of modification on biological processes:
cell cycle regulation ( 1 )

References 

1

Waraky A, et al. (2017) Nuclear insulin-like growth factor 1 receptor phosphorylates proliferating cell nuclear antigen and rescues stalled replication forks after DNA damage. J Biol Chem 292, 18227-18239
28924044   Curated Info