Ser485

Site Information
VLDIEQFsVVKGIYL SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 23111438

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 2 )
Disease tissue studied:	liver cancer ( 2 ) , hepatocellular carcinoma ( 2 )
Relevant cell line - cell type - tissue:	hepatocyte-liver ( 2 )

Upstream Regulation
Kinases, in vitro:	GRK4 (human) ( 1 )

References
1	Allen SJ, et al. (2015) Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4. J Biol Chem 290, 20360-73 26134571 Curated Info
2	Gu T (2009) CST Curation Set: 7560; Year: 2009; Biosample/Treatment: liver, hepatocyte/untreated; Disease: liver cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info

References

Allen SJ, et al. (2015) Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4. J Biol Chem 290, 20360-73
26134571 Curated Info

Gu T (2009) CST Curation Set: 7560; Year: 2009; Biosample/Treatment: liver, hepatocyte/untreated; Disease: liver cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info