Ser283

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Home > Phosphorylation Site Page: > Ser283 - CDX2 (human)

Site Information
RsVPEPLsPVSSLQA SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 456208

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	HCT116 (intestinal) ( 1 )

Upstream Regulation
Putative in vivo kinases:	CDK2 (human) ( 1 )
Kinases, in vitro:	CDK2 (human) ( 1 ) , GSK3B (human) ( 1 ) , P38A (human) ( 1 )

Downstream Regulation
Effects of modification on CDX2:	protein degradation ( 1 )

References
1	Gross I, et al. (2005) Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation. Oncogene 24, 7955-63 16027724 Curated Info

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