Ser409
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Home > Phosphorylation Site Page: > Ser409  -  URB (human)

Site Information
VITARRPsVsENLYP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 23071314

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 )
Disease tissue studied:
lung cancer ( 2 ) , mesothelioma ( 2 ) , non-small cell lung cancer ( 2 ) , non-small cell lung cancer, surrounding tissue ( 3 ) , non-small cell squamous cell lung carcinoma ( 2 )
Relevant cell line - cell type - tissue:
lung ( 3 ) , NCI-H226 (pulmonary) ( 2 )

Upstream Regulation
Kinases, in vitro:
PKG1 (human) ( 1 )

References 

1

Wang GR, et al. (2013) Steroid-sensitive Gene 1 Is a Novel Cyclic GMP-dependent Protein Kinase I Substrate in Vascular Smooth Muscle Cells. J Biol Chem 288, 24972-83
23831687   Curated Info

2

Rikova K (2011) CST Curation Set: 10904; Year: 2011; Biosample/Treatment: cell line, NCI-H226/untreated; Disease: non-small cell squamous cell lung carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY])
Curated Info

3

Rikova K (2008) CST Curation Set: 5354; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info