Thr86
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Home > Phosphorylation Site Page: > Thr86  -  PIK3R1 (cow)

Site Information
RKKIsPPtPKPRPPR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 22881800

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
BAEC (endothelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKCA (cow) ( 1 )
Treatments:
GF109203X ( 1 ) , phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on PIK3R1:
molecular association, regulation ( 1 )
Inhibit interaction with:
IRS1 (rat) ( 1 )

References 

1

Maeno Y, et al. (2012) Inhibition of Insulin Signaling in Endothelial Cells by Protein Kinase C-induced Phosphorylation of p85 Subunit of Phosphatidylinositol 3-Kinase (PI3K). J Biol Chem 287, 4518-30
22158866   Curated Info