Tyr398
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.0.1
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Tyr398  -  Spinophilin (mouse)

Site Information
DLVDVSAySGLGEDS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 22879101

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
CHO (fibroblast) ( 1 ) , platelet-blood ( 1 )

Upstream Regulation
Regulatory protein:
SHP-1 (human) ( 1 )
Treatments:
NSC-87877 ( 1 ) , PAR1-activating_peptide ( 1 ) , thrombin ( 1 ) , U46619 ( 1 )

Downstream Regulation
Effects of modification on Spinophilin:
molecular association, regulation ( 1 )
Induce interaction with:
SHP-1 (human) ( 1 )

References 

1

Ma P, et al. (2012) A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. Blood 119, 1935-45
22210881   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2019 Cell Signaling Technology, Inc.