Thr364
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Home > Phosphorylation Site Page: > Thr364  -  ELK1 (mouse)

Site Information
LLPTHTLtPVLLtPS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 22725902

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:
MEF (fibroblast) [ELK1 (mouse), homozygous knockout] ( 1 ) , MEF (fibroblast) ( 1 )

Upstream Regulation
Kinases, in vitro:
ERK2 (human) ( 1 )
Treatments:
phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on ELK1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )
Induce interaction with:
MED16 (mouse) ( 1 ) , MED23 (mouse) ( 1 ) , Trap100 (mouse) ( 1 )

References 

1

Mylona A, et al. (2016) Opposing effects of Elk-1 multisite phosphorylation shape its response to ERK activation. Science 354, 233-237
27738173   Curated Info

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