Tyr380

Site Information
YAGGrGsyGDLGGPI SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 456004

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 )
Relevant cell line - cell type - tissue:	brain ( 3 ) , kidney ( 3 ) , liver ( 1 ) , lung ( 3 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 2 ) , MEF (fibroblast) ( 2 ) , mpkCCD (renal) ( 4 ) , spleen ( 3 ) , testis ( 3 )

Upstream Regulation
Treatments:	desmopressin ( 4 )

References
1	Wilson-Grady JT, Haas W, Gygi SP (2013) Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation. Methods 61, 277-86 23567750 Curated Info
2	Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6 21659605 Curated Info
3	Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89 21183079 Curated Info
4	Rinschen MM, et al. (2010) Quantitative phosphoproteomic analysis reveals vasopressin V2-receptor-dependent signaling pathways in renal collecting duct cells. Proc Natl Acad Sci U S A 107, 3882-7 20139300 Curated Info