Tyr72

Site Information
IkALRtDyNAsVsVP SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 455999

In vivo Characterization
Methods used to characterize site in vivo:	2D analysis ( 1 ) , mass spectrometry ( 1 , 2 , 3 ) , western blotting ( 1 )
Disease tissue studied:	anthrax infection ( 2 )
Relevant cell line - cell type - tissue:	3T3 (fibroblast) ( 3 ) , HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 1 ) , spleen ( 2 )

Upstream Regulation
Treatments:	heat_shock ( 1 )

References
1	Kim HJ, et al. (2017) Heterogeneous nuclear ribonucleoprotein K inhibits heat shock-induced transcriptional activity of heat shock factor 1. J Biol Chem 292, 12801-12812 28592492 Curated Info
2	Manes NP, et al. (2011) Discovery of mouse spleen signaling responses to anthrax using label-free quantitative phosphoproteomics via mass spectrometry. Mol Cell Proteomics 10, M110.000927 21189417 Curated Info
3	Wang Z, Gucek M, Hart GW (2008) Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc. Proc Natl Acad Sci U S A 105, 13793-8 18779572 Curated Info