Ser7
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Home > Phosphorylation Site Page: > Ser7  -  SET (mouse)

Site Information
_MAPKRQsAILPQPK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455972

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 , 4 , 5 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
lymphoma ( 5 ) , B cell lymphoma ( 5 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 3 ) , alphaT3-1 (pituitary cell) ( 1 ) , Hepa 1-6 (epithelial) ( 4 ) , LbetaT2 ( 1 ) , RAW 264.7 (macrophage) ( 2 ) , WEHI-231 (B lymphocyte) ( 5 )

Upstream Regulation
Regulatory protein:
GNRH1 (human) ( 1 )

Downstream Regulation
Effects of modification on SET:
protein degradation ( 1 )

References 

1

Avet C, et al. (2018) GnRH regulates the expression of its receptor accessory protein SET in pituitary gonadotropes. PLoS One 13, e0201494
30052687   Curated Info

2

Pinto SM, et al. (2015) Quantitative phosphoproteomic analysis of IL-33-mediated signaling. Proteomics 15, 532-44
25367039   Curated Info

3

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info

4

Pan C, Gnad F, Olsen JV, Mann M (2008) Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors. Proteomics 8, 4534-46
18846507   Curated Info

5

Shu H, et al. (2004) Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line. Mol Cell Proteomics 3, 279-86
14729942   Curated Info

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