Ser180
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Home > Phosphorylation Site Page: > Ser180  -  RAP1B (human)

Site Information
GkARKKsscQLL___   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 22689703

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , electrophoretic mobility shift ( 2 ) , immunoprecipitation ( 1 , 2 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
PKACA (human) ( 2 )

Downstream Regulation
Effects of modification on RAP1B:
molecular association, regulation ( 1 )
Inhibit interaction with:
RAP1GDS1 (human) ( 1 )

References 

1

Wilson JM, et al. (2016) Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B. J Mol Biol 428, 4929-4945
27760305   Curated Info

2

Altschuler D, Lapetina EG (1993) Mutational analysis of the cAMP-dependent protein kinase-mediated phosphorylation site of Rap1b. J Biol Chem 268, 7527-31
8463283   Curated Info