Ser597

Site Information
RssGstRsDGGAGRT SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 22682200

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 2 ) , western blotting ( 2 )
Disease tissue studied:	bone cancer ( 2 ) , Ewing's sarcoma ( 2 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 2 ) , Rat2 (fibroblast) ( 2 ) , TC-32 ( 2 )

Downstream Regulation
Effects of modification on biological processes:	cytoskeletal reorganization ( 2 ) , transcription, inhibited ( 2 )

References
1	Nielsen CP, et al. (2019) USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification. Cell Rep 28, 1074-1089.e5 31340145 Curated Info
2	González-Sancho JM, et al. (2013) Functional Consequences of Wnt-induced Dishevelled 2 Phosphorylation in Canonical and Noncanonical Wnt Signaling. J Biol Chem 288, 9428-37 23396967 Curated Info