Ser245
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Home > Phosphorylation Site Page: > Ser245  -  E2A (human)

Site Information
PMLGGGSsPLPLPPG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455906

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
lymphoma ( 1 ) , B cell lymphoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
CDK2 (human) ( 1 ) , CDK4 (human) ( 1 )

Downstream Regulation
Effects of modification on biological processes:
cell growth, altered ( 1 )

References 

1

Chu C, Kohtz DS (2001) Identification of the E2A gene products as regulatory targets of the G1 cyclin-dependent kinases. J Biol Chem 276, 8524-34
11114297   Curated Info