Thr1589

Site Information
FSMLDHLtQWARHKF SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 22561303

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phosphopeptide mapping ( 1 )
Disease tissue studied:	colorectal cancer ( 1 ) , colorectal carcinoma ( 1 )
Relevant cell line - cell type - tissue:	HCT116 (intestinal) ( 1 )

Downstream Regulation
Effects of modification on biological processes:	cell cycle regulation ( 1 ) , cell growth, induced ( 1 )

References
1	Nam EA, Zhao R, Cortez D (2011) Analysis of mutations that dissociate G(2) and essential S phase functions of human ataxia telangiectasia-mutated and Rad3-related (ATR) protein kinase. J Biol Chem 286, 37320-7 21908846 Curated Info