Tyr413

Site Information
ERDEEyGyECLDGKD SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 455818

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 2 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:	'brain, hippocampus' [GABRG2 (mouse), genetic knockin] ( 2 ) , 'neuron, hippocampal'-brain ( 1 )

Downstream Regulation
Effects of modification on GABRG2:	activity, induced ( 2 ) , receptor internalization, altered ( 2 )

References
1	Jurd R, et al. (2010) Fyn kinase contributes to tyrosine phosphorylation of the GABA(A) receptor gamma2 subunit. Mol Cell Neurosci 44, 129-34 20233604 Curated Info
2	Tretter V, et al. (2009) Deficits in spatial memory correlate with modified {gamma}-aminobutyric acid type A receptor tyrosine phosphorylation in the hippocampus. Proc Natl Acad Sci U S A 106, 20039-44 19903874 Curated Info