Tyr106
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Home > Phosphorylation Site Page: > Tyr106  -  MOR-1 (rat)

Site Information
MKtAtNIyIFNLALA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455804

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 , 2 )
Relevant cell line - cell type - tissue:
oocyte ( 2 ) , oocyte [CPEB (mouse)] ( 1 )

Downstream Regulation
Effects of modification on MOR-1:
activity, inhibited ( 1 )

References 

1

McLaughlin JP, Chavkin C (2001) Tyrosine phosphorylation of the mu-opioid receptor regulates agonist intrinsic efficacy. Mol Pharmacol 59, 1360-8
11353794   Curated Info

2

Celver JP, et al. (2001) Threonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytes. J Biol Chem 276, 4894-900
11060299   Curated Info