Ser271
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Home > Phosphorylation Site Page: > Ser271  -  rabphilin 3A (mouse)

Site Information
AGLRRANsVQAARPA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455801

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 2 , 3 , 4 , 5 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 , 6 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'brain, cerebral cortex' ( 5 ) , brain ( 2 , 3 , 4 ) , neutrophil ( 1 )

Upstream Regulation
Regulatory protein:
RAB3A (mouse) ( 6 )
Kinases, in vitro:
PKN1 (mouse) ( 1 )
Treatments:
depolarization ( 6 )

Downstream Regulation
Effects of modification on rabphilin 3A:
intracellular localization ( 1 , 6 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 1 )

References 

1

Yuan Q, et al. (2017) PKN1 Directs Polarized RAB21 Vesicle Trafficking via RPH3A and Is Important for Neutrophil Adhesion and Ischemia-Reperfusion Injury. Cell Rep 19, 2586-2597
28636945   Curated Info

2

Trinidad JC, et al. (2012) Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse. Mol Cell Proteomics 11, 215-29
22645316   Curated Info

3

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

4

Wiƛniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9
20415495   Curated Info

5

Munton RP, et al. (2007) Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics 6, 283-93
17114649   Curated Info

6

Foletti DL, Blitzer JT, Scheller RH (2001) Physiological modulation of rabphilin phosphorylation. J Neurosci 21, 5473-83
11466418   Curated Info