Ser533
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Home > Phosphorylation Site Page: > Ser533  -  CLASP2 (human)

Site Information
QGCsREAsREssRDT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 22349885

In vivo Characterization
Methods used to characterize site in vivo:
2D analysis ( 2 ) , mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
GSK3B (human) ( 2 )
Kinases, in vitro:
GSK3B (human) ( 2 )
Treatments:
SB216763 ( 2 ) , SB415286 ( 2 ) , siRNA ( 2 )

Downstream Regulation
Effects of modification on CLASP2:
intracellular localization ( 2 ) , molecular association, regulation ( 2 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 2 )
Inhibit interaction with:
EB1 (human) ( 2 ) , IQGAP1 (human) ( 2 )

References 

1

Christensen GL, et al. (2010) Quantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonists. Mol Cell Proteomics 9, 1540-53
20363803   Curated Info

2

Watanabe T, et al. (2009) Phosphorylation of CLASP2 by GSK-3beta regulates its interaction with IQGAP1, EB1 and microtubules. J Cell Sci 122, 2969-79
19638411   Curated Info