Ser219
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Home > Phosphorylation Site Page: > Ser219  -  PRKD1 (human)

Site Information
VSTIRtSsAELstsA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455755

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 ) , phospho-antibody ( 3 )
Disease tissue studied:
lung cancer ( 1 ) , non-small cell lung adenocarcinoma ( 1 ) , prostate cancer ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
Go_6976 ( 3 ) , Go_6983 ( 3 ) , H2O2 ( 3 )

Downstream Regulation
Effects of modification on PRKD1:
molecular association, regulation ( 3 )
Induce interaction with:
14-3-3 beta (human) ( 3 )

References 

1

Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. J Proteomics 91, 286-96
23911959   Curated Info

2

Chen L, Giorgianni F, Beranova-Giorgianni S (2010) Characterization of the phosphoproteome in LNCaP prostate cancer cells by in-gel isoelectric focusing and tandem mass spectrometry. J Proteome Res 9, 174-8
20044836   Curated Info

3

Zhang W, Zheng S, Storz P, Min W (2005) Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor. J Biol Chem 280, 19036-44
15755722   Curated Info