Ser104
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Home > Phosphorylation Site Page: > Ser104  -  PEA-15 (hamster)

Site Information
TKLTRIPsAKKYKDI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455750

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 1 ) , T lymphocyte-thymus ( 1 )

Upstream Regulation
Kinases, in vitro:
PKCA (human) ( 1 )
Treatments:
phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on PEA-15:
molecular association, regulation ( 1 )
Inhibit interaction with:
ERK1 (human) ( 1 ) , ERK2 (human) ( 1 )

References 

1

Renganathan H, Vaidyanathan H, Knapinska A, Ramos JW (2005) Phosphorylation of PEA-15 switches its binding specificity from ERK/MAPK to FADD. Biochem J 390, 729-35
15916534   Curated Info