Thr890
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Home > Phosphorylation Site Page: > Thr890  -  gp130 (human)

Site Information
GQVERFEtVGMEAAt   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455688

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 )
Disease tissue studied:
gastric cancer ( 1 ) , gastric carcinoma ( 1 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 2 ) , HepG2 (hepatic) ( 2 ) , MKN-45 (gastric) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKCD (human) ( 2 )
Kinases, in vitro:
PKCD (human) ( 2 )

Downstream Regulation
Effects of modification on gp130:
molecular association, regulation ( 2 )

References 

1

Moritz A (2010) CST Curation Set: 10616; Year: 2010; Biosample/Treatment: cell line, MKN-45/DMSO; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY])
Curated Info

2

Novotny-Diermayr V, Zhang T, Gu L, Cao X (2002) Protein kinase C delta associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp130 interaction. J Biol Chem 277, 49134-42
12361954   Curated Info

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