Ser70
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Home > Phosphorylation Site Page: > Ser70  -  Src (human)

Site Information
LFGGFNssDtVtsPQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2192576

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 2 , 3 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
PIK3CG (human) ( 1 )

Downstream Regulation
Effects of modification on Src:
enzymatic activity, induced ( 1 ) , receptor internalization, induced ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )

References 

1

Watson LJ, et al. (2016) Phosphorylation of Src by phosphoinositide 3-kinase regulates beta-adrenergic receptor-mediated EGFR transactivation. Cell Signal 28, 1580-92
27169346   Curated Info

2

Schreiber TB, et al. (2010) An integrated phosphoproteomics work flow reveals extensive network regulation in early lysophosphatidic acid signaling. Mol Cell Proteomics 9, 1047-62
20071362   Curated Info

3

Wissing J, et al. (2007) Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry. Mol Cell Proteomics 6, 537-47
17192257   Curated Info