Thr18
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.9
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Thr18  -  IEX-1 (human)

Site Information
MTILQAPtPAPSTIP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455559

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
leukemia ( 1 ) , acute myelogenous leukemia ( 1 )
Relevant cell line - cell type - tissue:
CHO (fibroblast) ( 1 ) , HeLa (cervical) ( 1 ) , UT-7 (myeloid) ( 1 )

Upstream Regulation
Putative in vivo kinases:
ERK2 (human) ( 1 )
Kinases, in vitro:
ERK2 (human) ( 1 )
Treatments:
PD98059 ( 1 ) , TPO ( 1 )

Downstream Regulation
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )

References 

1

Garcia J, et al. (2002) IEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation. EMBO J 21, 5151-63
12356731   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2024 Cell Signaling Technology, Inc.