Ser407
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Home > Phosphorylation Site Page: > Ser407  -  STAT6 (human)

Site Information
PIQLQALsLPLVVIV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 21561700

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , MEF (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:
TBK1 (human) ( 1 )
Kinases, in vitro:
TBK1 (human) ( 1 )
Treatments:
virus infection ( 1 )

Downstream Regulation
Effects of modification on STAT6:
intracellular localization ( 1 ) , molecular association, regulation ( 1 ) , phosphorylation ( 1 )
Effects of modification on biological processes:
signaling pathway regulation ( 1 ) , transcription, induced ( 1 )
Induce interaction with:
STAT6 (human) ( 1 )

References 

1

Chen H, et al. (2011) Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity. Cell 147, 436-46
22000020   Curated Info