Thr34

Javascript is not enabled on this browser. This site will not work properly without Javascript.

Home > Phosphorylation Site Page: > Thr34 - Akt1 (rat)

Site Information
FLLKNDGtFIGYKER SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 455493

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	L6 (myoblast) ( 1 )

Upstream Regulation
Kinases, in vitro:	PKCZ (rat) ( 1 )
Treatments:	ceramide ( 1 ) , Ro31-8220 ( 1 )

Downstream Regulation
Effects of modification on Akt1:	enzymatic activity, inhibited ( 1 )

References
1	Powell DJ, Hajduch E, Kular G, Hundal HS (2003) Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism. Mol Cell Biol 23, 7794-808 14560023 Curated Info

Developed with grants from

and literature mining with Linguamatics

PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.