Ser23
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Home > Phosphorylation Site Page: > Ser23  -  NKX2-1 (mouse)

Site Information
ILSPLEEsYKKVGME   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 21478902

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
KPC ( 1 )

Upstream Regulation
Putative in vivo kinases:
PLK1 (human) ( 1 )
Kinases, in vitro:
PLK1 (human) ( 1 )
Treatments:
GSK461364A ( 1 )

Downstream Regulation
Effects of modification on NKX2-1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
carcinogenesis, induced ( 1 ) , cell growth, induced ( 1 ) , transcription, induced ( 1 )
Induce interaction with:
DNA ( 1 )

References 

1

Kong Y, et al. (2022) The kinase PLK1 promotes the development of /-mutant lung adenocarcinoma through transcriptional activation of the receptor RET. Sci Signal 15, eabj4009
36194647   Curated Info